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Liver & Detox

Fatty Liver (NAFLD)

Reviewed by the Nimbera editorial team · Last updated May 2026

Non-alcoholic fatty liver disease (NAFLD) occurs when excess fat accumulates in liver cells of people who drink little or no alcohol. Left unmanaged it can progress to inflammation (NASH), fibrosis, and cirrhosis.

When to see a doctor

See a doctor if you have persistent fatigue or upper-right abdominal discomfort, if imaging or blood tests confirm NAFLD, if liver enzymes are elevated on repeat testing, or if you have diabetes or metabolic syndrome alongside liver findings.

Natural remedies · 6

Tap any remedy for the full how-to and citation.

How we rate evidence▾

Strong - Multiple randomised controlled trials or systematic reviews with consistent positive outcomes.

Moderate - At least one RCT or several high-quality observational studies with plausible mechanisms.

Limited - Small trials, animal studies, or traditional use with limited human clinical evidence.

Sources link directly to PubMed, Cochrane Reviews, or NCCIH.

Milk Thistle (Silymarin)

ingestible
A 2024 meta-analysis of 26 RCTs (2,375 patients) found silymarin significantly reduced ALT and AST and improved hepatic steatosis scores in NAFLD patients.
$15-$35 per month

Berberine

ingestible
A 2015 multicenter RCT (184 patients) found berberine plus lifestyle intervention reduced hepatic fat content by 52.7% vs 36.4% for lifestyle alone, with significant improvements in liver enzymes.
$20-$40 per month

Omega-3 Fish Oil

ingestible
A 2020 meta-analysis of 22 RCTs (1,366 participants) found omega-3 PUFA supplementation significantly reduced liver fat compared to placebo and improved liver enzymes.
$25-$50 per month for therapeutic doses

Vitamin E (Alpha-Tocopherol)

ingestible
The landmark PIVENS RCT (247 patients, 96 weeks) found vitamin E 800 IU/day was superior to placebo for improving steatosis, inflammation, ballooning, and resolution of steatohepatitis in non-diabetic NASH patients.
$10-$25 per month

Regular Aerobic Exercise

lifestyle
A 2023 systematic review found exercise training is 3.5 times more likely than standard care to achieve clinically meaningful liver fat reduction by MRI, independent of weight loss.
Free to low cost

Regular Coffee Consumption

lifestyle
A 2022 umbrella review found coffee consumption is inversely associated with NAFLD risk and liver fibrosis severity, with those drinking 2+ cups daily showing significantly lower liver stiffness scores.
$10-$30 per month (home brewing)

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Remedy information is compiled from primary clinical sources including PubMed, the Cochrane Library, and the National Center for Complementary and Integrative Health (NCCIH). Evidence ratings reflect published human trial data at time of writing. This content is for informational purposes only and is not a substitute for professional medical advice. Read our full disclaimer.