ingestible · for fatty liver (nafld)
Vitamin E (Alpha-Tocopherol)
Reviewed by the Nimbera editorial team · Last updated May 2026
How to use
Take 800 IU of natural alpha-tocopherol (d-alpha-tocopherol, not dl-alpha) daily with a fat-containing meal. This is a therapeutic dose - use only under medical supervision and for defined durations.
How it works
Vitamin E is a fat-soluble antioxidant that neutralizes reactive oxygen species generated during liver fat metabolism, reducing oxidative stress-driven inflammation and hepatocyte injury that drives NASH progression.
Where to buy
Pharmacies and health food stores. Look for natural d-alpha-tocopherol, not synthetic dl-alpha. Brands: NOW Foods, Solgar, Jarrow.
Typical cost: $10-$25 per month
Safety notes
High-dose vitamin E (800 IU+) should only be used under medical supervision. Long-term use above 400 IU/day has been associated with a slightly increased risk of prostate cancer in men. May increase bleeding risk with anticoagulants. Not recommended during pregnancy at high doses.
Drug & supplement interactions
- Always tell your doctor or pharmacist about any supplements you take.
- Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
- Herbal remedies can affect how the body absorbs or metabolises drugs.
- Check drugs.com interactions checker before starting.
Clinical source
PubMed - Sanyal et al. 2010 (PIVENS)This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.