ingestible · for fatty liver (nafld)
Milk Thistle (Silymarin)
Reviewed by the Nimbera editorial team · Last updated May 2026
How to use
Take 140-280 mg of standardized silymarin extract (70-80% silymarin content) 2-3 times daily with meals. Allow 8-12 weeks to assess response.
How it works
Silymarin acts as a potent antioxidant and anti-inflammatory agent, protecting liver cell membranes from oxidative damage, inhibiting inflammatory signaling, and stimulating liver cell regeneration.
Where to buy
Health food stores, pharmacies, Amazon - look for standardized 70-80% silymarin extract. Brands: Thorne, NOW Foods, Jarrow Formulas.
Typical cost: $15-$35 per month
Safety notes
Generally well tolerated. May cause mild GI upset. Can interact with certain medications metabolized by the liver - consult your doctor if on prescription drugs. Not recommended during pregnancy.
Drug & supplement interactions
- Always tell your doctor or pharmacist about any supplements you take.
- Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
- Herbal remedies can affect how the body absorbs or metabolises drugs.
- Check drugs.com interactions checker before starting.
Clinical source
PubMed - Federico et al. 2024This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.