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ingestible · for eczema & atopic dermatitis

Probiotics (Lactobacillus rhamnosus)

Reviewed by the Nimbera editorial team · Last updated May 2026

Voigt & Lele 2022 Am J Clin Dermatol (PMID 36161401) - Meta-analysis of 11 RCTs found perinatal Lactobacillus rhamnosus supplementation reduced atopic dermatitis incidence in infants with RR 0.60 (95% CI 0.47-0.75; p < 0.00001) at 2 years and RR 0.62 (95% CI 0.50-0.75; p < 0.00001) at 6-7 years follow-up.$20-30/month

How to use

For prevention in infants: mothers take L. rhamnosus GG (at least 10 billion CFU/day) from the last trimester of pregnancy through breastfeeding; infants given drops starting at birth for the first 6 months. For management in children with existing eczema: 5-10 billion CFU of L. rhamnosus GG daily for a minimum of 8 weeks. Take with or just before a meal to improve survival through stomach acid.

How it works

L. rhamnosus colonizes the gut and modulates immune development by promoting regulatory T-cell differentiation and shifting the immune response away from the Th2-dominant allergic phenotype associated with atopic dermatitis. It also strengthens gut barrier integrity, reducing systemic antigen exposure that can trigger skin inflammation.

Where to buy

Culturelle Digestive Daily Probiotic (L. rhamnosus GG, 10B CFU, ~$22 / 30 capsules), Florastor Kids Daily Probiotic Supplement (~$24 / 30 sachets), Gerber Soothe Probiotic Colic Drops for infants (~$26 / 0.34 oz). Look specifically for Lactobacillus rhamnosus GG (LGG) strain on the label for the most evidence-based option.

Typical cost: $20-30/month

Safety notes

Generally recognized as safe, but use caution in immunocompromised individuals, those with central venous catheters, or premature infants - consult a physician first. Quality varies significantly between brands; look for third-party tested products with guaranteed CFU counts through expiry. Probiotics do not replace established eczema treatments; evidence is strongest for prevention, not treatment.

Drug & supplement interactions

  • Always tell your doctor or pharmacist about any supplements you take.
  • Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
  • Herbal remedies can affect how the body absorbs or metabolises drugs.
  • Check drugs.com interactions checker before starting.

Clinical source

Voigt & Lele 2022 - Am J Clin Dermatol (PMID 36161401)

This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.