ingestible · for insomnia & trouble falling asleep
Magnesium Glycinate
Reviewed by the Nimbera editorial team · Last updated May 2026
How to use
Take 200-400mg magnesium glycinate 30-60 minutes before bed. Start at 200mg.
How it works
Magnesium activates GABA receptors (the same receptor system targeted by prescription sleep medications) and regulates nervous system excitability. Glycinate form is well-absorbed and less likely to cause digestive upset than magnesium oxide.
Where to buy
Health food stores and pharmacies. Pure Encapsulations, Thorne, and Doctor's Best make well-tested glycinate forms.
Typical cost: $15-35
Safety notes
High doses cause loose stools - start low and increase slowly. Not for people with kidney disease. Space 2+ hours from antibiotics and other medications.
Drug & supplement interactions
- Always tell your doctor or pharmacist about any supplements you take.
- Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
- Herbal remedies can affect how the body absorbs or metabolises drugs.
- Check drugs.com interactions checker before starting.
This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.