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ingestible · for uti prevention

Cranberry (Proanthocyanidins)

Reviewed by the Nimbera editorial team · Last updated May 2026

Fu et al. (2017, PMID 29046404) meta-analysis of 7 RCTs (n=1,498) found cranberry reduced UTI recurrence risk by 26% (pooled RR 0.74; 95% CI 0.55-0.98) in otherwise healthy women. Active component is type-A proanthocyanidins (PACs); juice and capsule forms both studied.$20-$50 per month for standardised PAC capsules

How to use

Take a standardised cranberry extract providing at least 36 mg of type-A proanthocyanidins (PACs) daily, or drink 8-10 oz of unsweetened cranberry juice twice daily. Capsules are preferred over juice to avoid excess sugar.

How it works

Type-A PACs in cranberry prevent E. coli from adhering to uroepithelial cell receptors by blocking fimbriae (hair-like appendages the bacteria use to attach to the bladder wall), allowing them to be flushed out with urination.

Where to buy

Pharmacies and supplement retailers; look for products listing PAC content (36 mg/day is the studied threshold). Brands include Ellura, Theracran, and Cysticlean.

Typical cost: $20-$50 per month for standardised PAC capsules

Safety notes

Not a treatment for active UTI. High doses of cranberry supplements may interact with warfarin (blood thinner) - consult a doctor if anticoagulated. Juice forms are high in sugar and calories. Evidence is less robust in men, catheterised patients, and children.

Drug & supplement interactions

  • Always tell your doctor or pharmacist about any supplements you take.
  • Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
  • Herbal remedies can affect how the body absorbs or metabolises drugs.
  • Check drugs.com interactions checker before starting.

Clinical source

Fu Z et al., Cranberry Reduces the Risk of UTI Recurrence in Otherwise Healthy Women: A Systematic Review and Meta-Analysis, J Nutr, 2017

This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.