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topical · for minor cuts, scrapes & wounds

Aloe Vera Gel (Wound Healing)

Reviewed by the Nimbera editorial team · Last updated May 2026

A systematic review by Maenthaisong et al. (Burns, 2007; 4 trials, n=371) found aloe vera-treated burn wounds healed a mean of 8.79 days faster than controls (p=0.006). A 2022 meta-analysis confirmed aloe vera healed burns significantly faster than silver sulfadiazine (mean difference RR -1.34, p<0.001).$8-$20 per bottle

How to use

For best results use a pure aloe vera gel of at least 99% aloe content (or direct fresh gel from an Aloe barbadensis leaf). Clean the wound first. Apply a thin layer of cool aloe gel to minor burns, abrasions, and superficial wounds 3-4 times daily. Do not cover tightly - allow to air or cover lightly with non-adherent gauze. Refrigerating the gel adds a soothing cooling effect.

How it works

Aloe vera gel contains acemannan (a bioactive polysaccharide) that stimulates macrophage activity, promotes fibroblast proliferation, and accelerates epithelialisation. It also contains salicylates (anti-inflammatory), anthraquinones (antimicrobial), and glycoproteins that reduce prostaglandin production and inhibit bradykinin-mediated pain.

Where to buy

Lily of the Desert Aloe Vera Gelly (99% aloe), Fruit of the Earth 100% Aloe Vera Gel, Seven Minerals Organic Aloe Vera Gel - available at Whole Foods, Target, Walmart, iHerb, and Amazon. Avoid products where aloe is listed low on the ingredient list or that contain high amounts of alcohol or fragrance.

Typical cost: $8-$20 per bottle

Safety notes

Perform a patch test first if you have sensitive skin - aloe can cause contact dermatitis in a small number of individuals. Do not apply to deep, infected, or surgical wounds without medical guidance. The latex fraction in whole-leaf aloe can irritate open wounds - only use inner-leaf gel or commercially purified products. Do not ingest aloe latex (the yellow sap). Keep away from eyes. Discontinue if the wound develops increased redness or swelling.

Drug & supplement interactions

  • Always tell your doctor or pharmacist about any supplements you take.
  • Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
  • Herbal remedies can affect how the body absorbs or metabolises drugs.
  • Check drugs.com interactions checker before starting.

Clinical source

Maenthaisong et al., Efficacy of aloe vera for burn wound healing: systematic review, Burns, 2007

This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.