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ingestible · for wound healing & tissue repair

Vitamin C (Wound Healing)

Reviewed by the Nimbera editorial team · Last updated May 2026

Bechara 2022 Antioxidants (PMID 36009324) - systematic review of 18 studies found vitamin C supplementation improved healing outcomes, predominantly in pressure ulcers; mechanistic role in collagen cross-linking is well established.$5-$15 for a month's supply of 500-1000 mg tablets

How to use

Supplement with 500-1000 mg of vitamin C daily while a wound is healing, taken with food to minimise stomach upset. Split into two doses if taking 1000 mg. Dietary sources such as citrus fruit, kiwi, bell peppers, and broccoli also contribute meaningfully. Continue for the duration of wound healing.

How it works

Vitamin C is an essential co-factor for prolyl and lysyl hydroxylase enzymes that stabilise the collagen triple helix. Without adequate vitamin C, new collagen is structurally weak. It also acts as an antioxidant in the wound microenvironment, reducing oxidative damage to newly forming tissue, and supports neutrophil function during the inflammatory phase of healing.

Where to buy

Widely available at pharmacies, supermarkets, and online as ascorbic acid tablets, buffered (calcium ascorbate) capsules, or powder. Standard ascorbic acid is the most cost-effective and well-studied form.

Typical cost: $5-$15 for a month's supply of 500-1000 mg tablets

Safety notes

Doses above 2000 mg/day may cause diarrhoea and gastrointestinal cramps. High-dose vitamin C (above 1000 mg/day) can interact with blood-thinning medications including warfarin - consult your doctor if you take anticoagulants. People prone to kidney stones (especially calcium oxalate stones) should not exceed 500 mg/day. Do not use as a substitute for medical wound care.

Drug & supplement interactions

  • Always tell your doctor or pharmacist about any supplements you take.
  • Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
  • Herbal remedies can affect how the body absorbs or metabolises drugs.
  • Check drugs.com interactions checker before starting.

Clinical source

Bechara 2022 - Antioxidants (PMID 36009324)

This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.