Skip to content
Back to Lower Back Pain

topical · for lower back pain

Topical Capsaicin Plaster

Reviewed by the Nimbera editorial team · Last updated May 2026

Keitel et al. (n=154) RCT: capsicum plaster over 3 weeks achieved 60.8% responder rate (>=30% pain reduction) vs 42.1% placebo (p=0.022); combined pain scores fell 38.5% vs 28.0% (p=0.002). PMID 11765591.$10-$25 for a pack of patches

How to use

Apply a capsaicin patch or plaster (0.025-0.075% capsaicin) to the painful area of the lower back. Leave in place as directed (typically 8-12 hours). Wash hands thoroughly after handling.

How it works

Capsaicin depletes substance P, a neuropeptide that transmits pain signals, from local sensory nerve endings. Repeated application produces sustained desensitisation of pain fibres in the treated area.

Where to buy

Pharmacies and supermarkets without a prescription. Low-concentration patches (Salonpas, Zostrix) are widely available. High-concentration patches (8%) require a clinic setting.

Typical cost: $10-$25 for a pack of patches

Safety notes

Causes a burning or stinging sensation on first application - this is normal and fades with continued use. Avoid contact with eyes and mucous membranes. Do not apply to broken skin.

Drug & supplement interactions

  • Always tell your doctor or pharmacist about any supplements you take.
  • Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
  • Herbal remedies can affect how the body absorbs or metabolises drugs.
  • Check drugs.com interactions checker before starting.

Clinical source

Keitel et al., Capsicum pain plaster in chronic non-specific low back pain, Arzneimittelforschung, 2001

This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.