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topical · for seborrheic dermatitis

Tea Tree Oil Shampoo (5%)

Reviewed by the Nimbera editorial team · Last updated May 2026

Satchell et al. 2002 single-blind RCT (n=126, Journal of the American Academy of Dermatology, PMID 12451368) found 5% tea tree oil shampoo produced a 41% improvement in dandruff severity score vs. 11% for placebo (P < 0.001), with no adverse effects.$8-$22 per bottle

How to use

Use a shampoo containing 5% tea tree oil 3-4 times per week. Work into a lather, leave on the scalp for 3-5 minutes, then rinse thoroughly. You can also add 2-3 drops of 100% tea tree oil to your regular shampoo per wash as a lower-cost alternative.

How it works

Terpinen-4-ol, the primary active component of tea tree oil (Melaleuca alternifolia), disrupts the cell membrane of Malassezia yeast and has broad antifungal and anti-inflammatory properties at concentrations as low as 0.25%.

Where to buy

Pharmacies and supermarkets (e.g., Thursday Plantation, Paul Mitchell Tea Tree, or pharmacy own-brand). Ensure the concentration is at or near 5% terpinen-4-ol.

Typical cost: $8-$22 per bottle

Safety notes

Tea tree oil is toxic if swallowed. Keep away from children. Undiluted oil can cause contact dermatitis - always use formulated shampoos or properly diluted solutions. Avoid contact with eyes.

Drug & supplement interactions

  • Always tell your doctor or pharmacist about any supplements you take.
  • Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
  • Herbal remedies can affect how the body absorbs or metabolises drugs.
  • Check drugs.com interactions checker before starting.

Clinical source

Satchell et al. 2002 - J Am Acad Dermatol (PMID 12451368)

This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.