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ingestible · for enlarged prostate (bph)

Stinging Nettle Root Extract

Reviewed by the Nimbera editorial team · Last updated May 2026

A 12-week RCT of 100 BPH patients found Urtica dioica root extract significantly improved IPSS scores, reduced PSA, and lowered inflammatory markers (CRP, MDA) versus placebo (Ghorbanibirgani et al. 2013).$12-$25 per month

How to use

Take 300-360 mg of standardized nettle root extract (Urtica dioica) twice daily. Often sold combined with saw palmetto or pygeum for additive benefit. Allow 6-8 weeks for effect.

How it works

Nettle root contains polysaccharides and lectins that bind to sex hormone-binding globulin (SHBG), reducing free testosterone available to prostate tissue. It also inhibits prostate cell proliferation and has anti-inflammatory effects on the prostatic stroma.

Where to buy

Health food stores and online - often found in prostate health blends; standalone root extract by NOW Foods, Gaia Herbs, or Herb Pharm

Typical cost: $12-$25 per month

Safety notes

Generally well tolerated. Ensure the product specifies root (radix), not aerial parts. May interact with blood pressure medications. Not appropriate as sole therapy for urinary retention.

Drug & supplement interactions

  • Always tell your doctor or pharmacist about any supplements you take.
  • Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
  • Herbal remedies can affect how the body absorbs or metabolises drugs.
  • Check drugs.com interactions checker before starting.

Clinical source

PubMed - Ghorbanibirgani et al. 2013

This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.