ingestible · for enlarged prostate (bph)
Pygeum (African Plum Bark Extract)
Reviewed by the Nimbera editorial team · Last updated May 2026
How to use
Take 100 mg once daily or 50 mg twice daily of standardized bark extract (13-14% triterpenes). Take with food. Give it at least 6-8 weeks before assessing response.
How it works
Pygeum bark contains phytosterols and triterpenes that reduce prostate stromal cell proliferation by downregulating TGF-beta-1 and FGF-2 signaling. It also has anti-inflammatory properties and reduces bladder contractility, easing urge symptoms.
Where to buy
Online retailers and natural health stores - look for brands like NOW Foods or Solaray with standardized extract (13% total sterols)
Typical cost: $15-$30 per month
Safety notes
Mild GI side effects possible. Not recommended as sole therapy for significant urinary obstruction. Sourcing practices matter - look for sustainably certified pygeum as overharvesting has threatened wild populations.
Drug & supplement interactions
- Always tell your doctor or pharmacist about any supplements you take.
- Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
- Herbal remedies can affect how the body absorbs or metabolises drugs.
- Check drugs.com interactions checker before starting.
Clinical source
PubMed - Wilt et al. 2002This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.