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ingestible · for enlarged prostate (bph)

Pumpkin Seed Extract

Reviewed by the Nimbera editorial team · Last updated May 2026

The GRANU randomized placebo-controlled trial (1,431 men, 12 months) found pumpkin seed produced a clinically relevant reduction in IPSS symptom scores versus placebo (Vahlensieck et al. 2015).$10-$25 per month for capsules; $5-$8 per month for seeds

How to use

Take 500 mg of standardized pumpkin seed extract twice daily, or eat 1-2 tablespoons of raw shelled pumpkin seeds daily. A 24-month study showed sustained benefit without loss of sexual function.

How it works

Pumpkin seeds are rich in delta-7-sterols and zinc, which inhibit 5-alpha-reductase activity and reduce DHT-driven prostate cell proliferation. The oil also reduces testosterone-induced prostate enlargement in animal models.

Where to buy

Health food stores for standardized capsules (Swanson, Jarrow, Natrol); raw pumpkin seeds available at grocery stores and bulk food retailers

Typical cost: $10-$25 per month for capsules; $5-$8 per month for seeds

Safety notes

Well tolerated with very few reported side effects. Does not appear to impair sexual function. Not recommended as sole therapy for severe obstructive symptoms.

Drug & supplement interactions

  • Always tell your doctor or pharmacist about any supplements you take.
  • Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
  • Herbal remedies can affect how the body absorbs or metabolises drugs.
  • Check drugs.com interactions checker before starting.

Clinical source

PubMed - Vahlensieck et al. 2015 (GRANU study)

This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.