ingestible · for high cholesterol support
Plant Sterols & Stanols
Reviewed by the Nimbera editorial team · Last updated May 2026
How to use
Consume 2 g of plant sterols or stanols per day from fortified foods (e.g., Benecol spreads, fortified orange juice, or supplement capsules). Split into two servings taken with meals for best effect.
How it works
Plant sterols and stanols are structurally similar to cholesterol. They compete with dietary cholesterol for absorption in the intestine, reducing the amount of cholesterol that enters the bloodstream.
Where to buy
Fortified margarines (Benecol, Flora ProActiv), fortified orange juice, or standalone supplement capsules available at pharmacies and health food stores.
Typical cost: $15-$30 per month for supplements; fortified foods vary by product.
Safety notes
Generally well tolerated. High doses (above 3 g/day) offer little additional benefit and may reduce absorption of fat-soluble vitamins (A, D, E, K) and carotenoids. Not recommended during pregnancy. Not a replacement for dietary changes or statins in high-risk individuals.
Drug & supplement interactions
- Always tell your doctor or pharmacist about any supplements you take.
- Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
- Herbal remedies can affect how the body absorbs or metabolises drugs.
- Check drugs.com interactions checker before starting.
Clinical source
Ras et al. Br J Nutr 2014 - PMID 24780090This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.