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topical · for motion sickness

Peppermint Oil Inhalation

Reviewed by the Nimbera editorial team · Last updated May 2026

Toniolo, Delaide & Beloni (2021, J Altern Complement Med, PMID 34283916) reviewed 11 studies on inhaled aromatherapy for nausea; 7 of 9 adult studies showed statistically significant results with direct inhalation, and peppermint was among the essential oils alleviating both nausea and vomiting. Studies were primarily in chemotherapy and postoperative contexts; direct RCT evidence for motion sickness specifically is limited.$8-$15 for a small bottle of pure essential oil (many uses). Inhaler sticks under $5.

How to use

Apply 1-2 drops of pure peppermint essential oil to a tissue or inhaler stick and inhale slowly through the nose for 30-60 seconds at the onset of nausea. Repeat as needed. Alternatively, apply a small amount to the temples or under the nose (avoid mucous membranes and eyes). Do not ingest undiluted essential oil.

How it works

Menthol, the primary active compound in peppermint oil, activates TRPM8 cold-sensing receptors and modulates 5-HT3 activity. Olfactory stimulation via inhalation appears to reduce vagally mediated gastric motility disturbances associated with nausea. The mechanism is rapid - effects are typically felt within minutes of inhalation.

Where to buy

Health food stores and pharmacies. Look for 100% pure peppermint essential oil (Mentha piperita). Personal aromatherapy inhalers (refillable sticks) make on-the-go use discreet and portable.

Typical cost: $8-$15 for a small bottle of pure essential oil (many uses). Inhaler sticks under $5.

Safety notes

Not safe for children under 2 years old - menthol can cause respiratory distress in infants. Avoid contact with eyes and mucous membranes. Do not ingest undiluted oil. People with G6PD deficiency should avoid menthol. Patch test diluted oil on skin before topical application. Not a substitute for medical antiemetics in severe nausea.

Drug & supplement interactions

  • Always tell your doctor or pharmacist about any supplements you take.
  • Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
  • Herbal remedies can affect how the body absorbs or metabolises drugs.
  • Check drugs.com interactions checker before starting.

Clinical source

Toniolo J, Delaide V & Beloni P, Effectiveness of Inhaled Aromatherapy on Chemotherapy-Induced Nausea and Vomiting: A Systematic Review, J Altern Complement Med, 2021

This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.