Skip to content
Back to Acute Bronchitis & Cough

ingestible · for acute bronchitis & cough

Pelargonium sidoides (EPs 7630)

Reviewed by the Nimbera editorial team · Last updated May 2026

Kardos et al. (2022) meta-analysis of 11 RCTs, n=2,195 participants; EPs 7630 produced a >=50% cough intensity response in 88.7% of patients vs. 47.6% in placebo group for acute bronchitis. Significant improvements also in quality of life and return to normal activities (PMID 36051888).$12-$20 for a 100 ml bottle sufficient for one treatment course.

How to use

Take EPs 7630 liquid extract (30 drops in water) or tablets 3 times daily between meals at the first sign of acute bronchitis. Continue for 7 days. Follow package directions for children's weight-adjusted dosing. The root extract is the studied form - not the whole plant.

How it works

EPs 7630 contains coumarins (umckalin, scopoletin) and polyphenols that act through multiple pathways: direct antiviral activity against influenza and rhinovirus, immunomodulation via increased interferon production, antibacterial activity preventing secondary infection, and secretolytic effects that facilitate sputum clearance.

Where to buy

Umcka (Nature's Way) is the primary branded product in North American pharmacies and online. Kaloba is the European branded equivalent. Look specifically for Pelargonium sidoides root extract, not other pelargonium species.

Typical cost: $12-$20 for a 100 ml bottle sufficient for one treatment course.

Safety notes

Rare reports of liver injury with prolonged use - limit to 7-10 days for acute bronchitis as studied. May interact with immunosuppressants. Avoid if you have a liver condition or are taking warfarin. Not studied in pregnancy. Some patients experience gastrointestinal upset.

Drug & supplement interactions

  • Always tell your doctor or pharmacist about any supplements you take.
  • Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
  • Herbal remedies can affect how the body absorbs or metabolises drugs.
  • Check drugs.com interactions checker before starting.

Clinical source

Kardos P et al., Effects of Pelargonium sidoides extract EPs 7630 on acute cough and quality of life: a meta-analysis of randomized, placebo-controlled trials, Multidiscip Respir Med, 2022

This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.