ingestible · for rosacea & facial redness
Omega-3 Fatty Acids (Fish Oil)
Reviewed by the Nimbera editorial team · Last updated May 2026
How to use
Take 2-3 grams of combined EPA and DHA daily with food to minimize fishy aftertaste. Choose triglyceride-form fish oil for better absorption. Use consistently for at least 3 months before assessing effect on skin redness.
How it works
EPA and DHA from omega-3 fatty acids competitively inhibit arachidonic acid metabolism, shifting the balance away from pro-inflammatory eicosanoids toward anti-inflammatory resolvins and protectins. They also attenuate LL-37-induced rosacea-like inflammation by suppressing TLR2/MyD88/NF-kB signaling that is abnormally activated in rosacea patients.
Where to buy
Fish oil capsules available at all pharmacies and health food stores; reputable brands include Nordic Naturals, Carlson, Thorne, and NOW Foods. Also available as algae-based omega-3 for vegetarians.
Typical cost: $20-$50 per month for a quality therapeutic-dose fish oil supplement
Safety notes
May cause fishy aftertaste or mild GI upset - take with food or use enteric-coated capsules. At high doses (above 3g/day) may mildly increase bleeding time - consult a doctor before use if on blood thinners.
Drug & supplement interactions
- Always tell your doctor or pharmacist about any supplements you take.
- Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
- Herbal remedies can affect how the body absorbs or metabolises drugs.
- Check drugs.com interactions checker before starting.
Clinical source
PubMed - Bhargava et al. 2016This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.