ingestible · for high cholesterol support
Omega-3 Fish Oil
Reviewed by the Nimbera editorial team · Last updated May 2026
How to use
Take 2-4 g of combined EPA and DHA daily with meals to minimize fishy aftertaste. Use enteric-coated or high-quality purified fish oil. Prescription-strength omega-3 (Vascepa, Lovaza) requires a doctor.
How it works
EPA and DHA reduce hepatic triglyceride synthesis and increase triglyceride clearance by enhancing lipoprotein lipase activity. They also reduce VLDL secretion from the liver and have anti-inflammatory effects on arterial walls.
Where to buy
Pharmacies, grocery stores, and online. Trusted brands include Nordic Naturals, Carlson, Kirkland Signature, and NOW Foods.
Typical cost: $15-$40 per month depending on dose and brand
Safety notes
High doses (above 3 g/day) may slightly increase LDL in some individuals - monitor levels. May have mild blood-thinning effects; consult your doctor if on anticoagulants. Avoid fish-derived oils if allergic to fish.
Drug & supplement interactions
- Always tell your doctor or pharmacist about any supplements you take.
- Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
- Herbal remedies can affect how the body absorbs or metabolises drugs.
- Check drugs.com interactions checker before starting.
Clinical source
PubMed - Harris et al. 2006This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.