Back to Uneven Skin Tone
topical · for uneven skin tone
Niacinamide (Vitamin B3) Serum
Reviewed by the Nimbera editorial team · Last updated May 2026
Strong evidence$7-35
How to use
Apply 4-10% niacinamide serum to clean skin morning and night. Pairs well with vitamin C and licorice.
How it works
Inhibits transfer of melanin from pigment-producing cells to skin surface. Multiple RCTs confirm effectiveness for facial hyperpigmentation.
Where to buy
Drugstores, Sephora, online. The Ordinary 10% Niacinamide is a popular budget option (~$7).
Typical cost: $7-35
Safety notes
Generally very gentle. Start with lower concentration if sensitive.
Drug & supplement interactions
- Always tell your doctor or pharmacist about any supplements you take.
- Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
- Herbal remedies can affect how the body absorbs or metabolises drugs.
- Check drugs.com interactions checker before starting.
Clinical source
Systematic Review (PMC)This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.