ingestible · for post-viral recovery (long covid)
N-Acetylcysteine (NAC)
Reviewed by the Nimbera editorial team · Last updated May 2026
How to use
Take 600 mg NAC once or twice daily on an empty stomach or with a light meal. Some practitioners use 600-1200 mg/day for post-viral recovery. Drink adequate water throughout the day.
How it works
NAC is a precursor to glutathione, the body's primary intracellular antioxidant. Post-viral illness depletes glutathione, allowing oxidative stress to impair mitochondria, damage endothelial cells, and sustain neuroinflammation. NAC also has mucolytic properties and helps regulate inflammatory cytokine signaling.
Where to buy
Health stores, pharmacies, Amazon. Brands: Thorne NAC, NOW Foods NAC, Life Extension NAC.
Typical cost: $15-$30 per month
Safety notes
Can interact with nitroglycerin and cause hypotension - avoid concurrent use. May reduce efficacy of some chemotherapy drugs. High doses (above 1800 mg/day) can cause nausea or GI upset. Asthmatics should start with low dose as it can occasionally trigger bronchospasm.
Drug & supplement interactions
- Always tell your doctor or pharmacist about any supplements you take.
- Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
- Herbal remedies can affect how the body absorbs or metabolises drugs.
- Check drugs.com interactions checker before starting.
Clinical source
PubMed - Bramante et al. 2025This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.