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ingestible · for thyroid support

Myo-Inositol plus Selenium

Reviewed by the Nimbera editorial team · Last updated May 2026

A 2017 randomized trial (Nordio and Basciani) found that 600 mg myo-inositol plus 83 mcg selenium daily restored a euthyroid TSH in Hashimoto's patients with subclinical hypothyroidism better than selenium alone.$20-$40 per month

How to use

Common regimen is 600 mg myo-inositol combined with 83 mcg selenium once daily, taken for about 6 months. Often sold as a single combination powder or capsule. Reassess TSH with your doctor after the course.

How it works

Myo-inositol is a second messenger in the TSH receptor signaling pathway, so restoring it can improve how thyroid cells respond to TSH. Paired with selenium's antioxidant and antibody-lowering effects, the combination targets both the signaling defect and the autoimmune inflammation of Hashimoto's.

Where to buy

Online and specialty pharmacies, often marketed for thyroid or fertility support. Example brands: Lo.Li Pharma Tirosel, Theralogix, Fairhaven Health MyoInositol combined with a separate selenium.

Typical cost: $20-$40 per month

Safety notes

Keep total selenium under 400 mcg/day if adding other selenium sources. Myo-inositol may cause mild nausea or loose stools at higher doses. Not a replacement for levothyroxine in overt hypothyroidism. Consult a doctor if pregnant, as inositol is also used in pregnancy for other reasons.

Drug & supplement interactions

  • Always tell your doctor or pharmacist about any supplements you take.
  • Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
  • Herbal remedies can affect how the body absorbs or metabolises drugs.
  • Check drugs.com interactions checker before starting.

This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.