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ingestible · for tinnitus

Melatonin

Reviewed by the Nimbera editorial team · Last updated May 2026

A randomized clinical trial (Hurtuk et al. 2011) found melatonin associated with a statistically significant decrease in tinnitus intensity and improved sleep quality in chronic tinnitus patients.$8-$18 per month

How to use

Take 3 mg melatonin 30-60 minutes before bedtime. Start with 1 mg if sensitive to supplements. Best suited for tinnitus sufferers who also experience sleep disruption.

How it works

Melatonin regulates the sleep-wake cycle, reducing nocturnal hyperactivation of auditory pathways. It also has antioxidant properties that may protect cochlear cells and dampen the central nervous system's amplification of tinnitus signals.

Where to buy

Pharmacies, grocery stores, Amazon - brands like Natrol, Nature Made, or Solgar. Available in immediate or extended-release formulas.

Typical cost: $8-$18 per month

Safety notes

May cause morning drowsiness, especially at doses above 3 mg. Not recommended during pregnancy or breastfeeding. Can interact with blood pressure medications and immunosuppressants. Use the lowest effective dose.

Drug & supplement interactions

  • Always tell your doctor or pharmacist about any supplements you take.
  • Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
  • Herbal remedies can affect how the body absorbs or metabolises drugs.
  • Check drugs.com interactions checker before starting.

Clinical source

PubMed - Hurtuk et al. 2011

This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.