ingestible · for stress & anxiety
Magnesium Glycinate
Reviewed by the Nimbera editorial team · Last updated May 2026
How to use
Take 200-400mg magnesium glycinate daily with food. Glycinate form is preferred for anxiety.
How it works
Magnesium regulates the HPA axis - the central stress response system. Deficiency is common and linked to heightened anxiety and irritability. Multiple clinical reviews support supplementation for anxiety reduction.
Where to buy
Health food stores and pharmacies. Avoid magnesium oxide - poorly absorbed. Pure Encapsulations Magnesium Glycinate is a well-tested option.
Typical cost: $15-30
Safety notes
High doses cause loose stools - start at 200mg and increase slowly. Not for kidney disease. Space 2+ hours from other medications.
Drug & supplement interactions
- Always tell your doctor or pharmacist about any supplements you take.
- Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
- Herbal remedies can affect how the body absorbs or metabolises drugs.
- Check drugs.com interactions checker before starting.
Clinical source
Nutrients (systematic review); NCCIHThis information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.