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ingestible · for men's health & prostate support

Lycopene

Reviewed by the Nimbera editorial team · Last updated May 2026

Zu et al. 2015 meta-analysis (Medicine, PMID 26287411) - 11 epidemiological studies and RCTs found higher lycopene intake associated with significantly lower prostate cancer risk (RR 0.81, 95% CI 0.72-0.91) and reduced PSA levels in men with early prostate changes. Concentrated dietary sources and supplements both show benefit.$0-$20/month (dietary-first approach costs nothing extra).

How to use

Target 10-30 mg/day of lycopene from dietary sources or supplements. Tomato paste and cooked tomato products are the richest sources (1/2 cup tomato paste = ~30 mg lycopene; 1 cup marinara = ~25 mg). Lycopene is fat-soluble - always consume with a source of fat for optimal absorption. Supplements: 10-15 mg/day of lycopene in softgels.

How it works

Lycopene is a powerful carotenoid antioxidant that reduces oxidative DNA damage in prostate cells, inhibits IGF-1-mediated cell proliferation, and may modulate androgen receptor signalling. Its accumulation in prostate tissue (lycopene concentrates in the prostate above all other organs) positions it uniquely for local cytoprotective effects.

Where to buy

Dietary sources: tomato products (paste, sauce, sun-dried tomatoes), watermelon, pink grapefruit, papaya. Supplements: Jarrow Formulas Lycopene ($15-$20/60 softgels), NOW Foods Lycopene ($10-$15/60 softgels) - at pharmacies and health food stores.

Typical cost: $0-$20/month (dietary-first approach costs nothing extra).

Safety notes

Dietary lycopene from food is extremely safe. Caution at very high supplement doses (>120 mg/day): lycopenodermia (orange skin discolouration - harmless but cosmetically notable). Theoretically may interact with some cholesterol medications at high doses. If you have prostate cancer, discuss lycopene with your oncologist before supplementing.

Drug & supplement interactions

  • Always tell your doctor or pharmacist about any supplements you take.
  • Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
  • Herbal remedies can affect how the body absorbs or metabolises drugs.
  • Check drugs.com interactions checker before starting.

Clinical source

Zu et al. 2015 - Medicine (PMID 26287411)

This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.