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ingestible · for enlarged prostate (bph)

Lycopene (Tomato Carotenoid)

Reviewed by the Nimbera editorial team · Last updated May 2026

A 6-month RCT (40 men) found 15 mg/day lycopene prevented prostate enlargement on ultrasound and reduced PSA levels versus placebo, where prostate size increased (Schwarz et al. 2008).$10-$20 per month for supplements

How to use

Take 15 mg of lycopene daily from a supplement, or consume cooked tomato products daily (cooked tomatoes, tomato paste, and tomato sauce significantly increase lycopene bioavailability versus raw). Pair with a fat source to improve absorption.

How it works

Lycopene accumulates in prostate tissue and inhibits androgen receptor signaling, IGF-1 pathways, and IL-6 expression - all of which drive prostate cell proliferation. Its potent antioxidant activity also reduces oxidative stress in the gland.

Where to buy

Supplement form at pharmacies and online (Jarrow, Solgar, Lyc-O-Mato brand); dietary sources include tomato paste, tomato sauce, watermelon, and pink grapefruit

Typical cost: $10-$20 per month for supplements

Safety notes

Very safe at 15 mg/day; no significant adverse effects reported in clinical trials. Evidence base is still small. Should not replace medical monitoring for prostate disease. Men with prostate cancer should consult their oncologist before supplementing.

Drug & supplement interactions

  • Always tell your doctor or pharmacist about any supplements you take.
  • Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
  • Herbal remedies can affect how the body absorbs or metabolises drugs.
  • Check drugs.com interactions checker before starting.

Clinical source

PubMed - Schwarz et al. 2008

This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.