ingestible · for cravings & habit-breaking
L-Glutamine
Reviewed by the Nimbera editorial team · Last updated May 2026
How to use
Mix 5-10 g of L-glutamine powder in water and drink when a sugar craving hits, or take 5 g three times daily between meals. Some practitioners suggest holding a small amount under the tongue briefly before swallowing.
How it works
Glutamine is the primary fuel for intestinal epithelial cells and helps maintain gut lining integrity, reducing inflammation linked to dysregulated appetite. It also stimulates GLP-1 release which signals satiety, and provides a quick brain energy source that may blunt acute sugar cravings.
Where to buy
Health food stores, Amazon, supplement retailers. Sold as unflavored powder or capsules. Buy pharmaceutical grade where possible.
Typical cost: $15-30/month
Safety notes
Generally well-tolerated. Avoid if you have liver disease, kidney disease, or seizure disorder. High doses (over 30 g/day) may cause GI discomfort. Not for use by people with certain cancers without physician guidance.
Drug & supplement interactions
- Always tell your doctor or pharmacist about any supplements you take.
- Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
- Herbal remedies can affect how the body absorbs or metabolises drugs.
- Check drugs.com interactions checker before starting.
Clinical source
PubMed - Greenfield et al. 2021This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.