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ingestible · for spider veins

Horse Chestnut Extract

Reviewed by the Nimbera editorial team · Last updated May 2026

Moderate (for symptoms, not appearance)$15-30

How to use

Take standardized extract with 16-20% aescin, typically 300mg twice daily. Available oral or topical cream.

How it works

Aescin strengthens vein walls, reduces venous congestion, and decreases swelling. Cochrane review found it effective for chronic venous insufficiency symptoms - but limited evidence specifically for spider vein appearance.

Where to buy

Health stores, supplement retailers (Venastat is a common brand).

Typical cost: $15-30

Safety notes

Raw seeds are TOXIC - only use processed extracts. Can interact with blood thinners. Side effects include nausea, dizziness. Not for pregnancy/breastfeeding.

Drug & supplement interactions

  • Always tell your doctor or pharmacist about any supplements you take.
  • Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
  • Herbal remedies can affect how the body absorbs or metabolises drugs.
  • Check drugs.com interactions checker before starting.

Clinical source

Cochrane Library; Vein Center

This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.