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ingestible · for motion sickness

Ginger Root Extract (Zingiber officinale)

Reviewed by the Nimbera editorial team · Last updated May 2026

Nunes et al. (2020, Curr Ther Res, PMID 32714473) conducted an open-label study (n=174) using 160 mg Zingiber officinale extract containing 8 mg gingerols. Significant reductions in Motion Sickness Assessment Questionnaire total scores were seen across three post-treatment trips (p<0.0001). Note: NCCIH states most RCTs for motion sickness specifically have not shown significant benefit; evidence is stronger for pregnancy nausea.$8-$20 for a travel-size supply of capsules. Ginger candies under $5.

How to use

Take 250-500 mg of standardised ginger root extract 30-60 minutes before travel. Some people prefer fresh ginger tea or ginger candies - use at least 1 g equivalent of fresh ginger per serving. Repeat every 4 hours during extended travel if needed.

How it works

Gingerols and shogaols, the active compounds in ginger, are thought to act on 5-HT3 receptors in the gut and brainstem (the same receptors targeted by pharmaceutical antiemetics), dampening the nausea signalling pathway. Ginger also appears to reduce gastric tachyarrhythmia - the abnormal stomach rhythm that accompanies motion sickness.

Where to buy

Pharmacies and supermarkets. Look for standardised extracts listing gingerol content. Ginger candies (e.g., Gin-Gins) and ginger tea are widely available alternatives.

Typical cost: $8-$20 for a travel-size supply of capsules. Ginger candies under $5.

Safety notes

Can cause heartburn, abdominal discomfort, or mouth irritation at higher doses. May have mild antiplatelet effects - use caution if taking blood-thinning medications. Evidence for motion sickness specifically is weaker than for pregnancy-related nausea; it is best used as a complement to other strategies rather than a standalone treatment.

Drug & supplement interactions

  • Always tell your doctor or pharmacist about any supplements you take.
  • Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
  • Herbal remedies can affect how the body absorbs or metabolises drugs.
  • Check drugs.com interactions checker before starting.

Clinical source

Nunes CP et al., Clinical Evaluation of the Use of Ginger Extract in the Preventive Management of Motion Sickness, Curr Ther Res Clin Exp, 2020

This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.