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Chromium Picolinate

Reviewed by the Nimbera editorial team · Last updated May 2026

Docherty et al. 2005 double-blind RCT found 600 mcg/day significantly reduced carbohydrate craving scores in patients with atypical depression vs. placebo.$8-18/month

How to use

Take 200-1000 mcg chromium picolinate daily with food, starting at the lower end. Most RCTs used 600-1000 mcg. Take consistently for at least 8 weeks to assess effect.

How it works

Chromium enhances insulin signaling by activating insulin receptor tyrosine kinase, improving glucose uptake into cells. Steadier blood sugar reduces the sharp glucose dips that trigger carbohydrate and sugar cravings.

Where to buy

Pharmacies, health food stores, Amazon, Costco. Look for chromium picolinate specifically - it has the best absorption of chromium forms.

Typical cost: $8-18/month

Safety notes

May lower blood sugar - monitor carefully if diabetic or on glucose-lowering medications. High doses (over 1000 mcg/day) not well studied long-term. Avoid if kidney disease is present.

Drug & supplement interactions

  • Always tell your doctor or pharmacist about any supplements you take.
  • Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
  • Herbal remedies can affect how the body absorbs or metabolises drugs.
  • Check drugs.com interactions checker before starting.

This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.