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Bacopa Monnieri (Brahmi)

Reviewed by the Nimbera editorial team · Last updated May 2026

Stough et al. 2001 RCT (Psychopharmacology, PMID 11498727) - 76 healthy adults taking 300 mg/day bacopa or placebo for 12 weeks showed significant improvements in verbal learning, memory consolidation, and rate of learning at 12 weeks versus placebo. Effect size was moderate.$15-$30/month.

How to use

Take 300-450 mg/day of a standardised extract (20-55% bacosides) with food - fat aids absorption. Split into two doses. Allow 8-12 weeks for full effect; bacopa works slowly but effects are sustained.

How it works

Bacosides A and B (active saponins) enhance synaptic transmission in the hippocampus, upregulate serotonin transporter activity, and reduce cortisol-related memory impairment. Bacopa also has antioxidant effects on brain tissue and may enhance acetylcholine signalling.

Where to buy

Himalaya Bacopa ($15-$20/60 tablets), Jarrow Formulas Brahmi ($20-$25/60 capsules), Nootropics Depot Bacopa - widely available online and at health food stores.

Typical cost: $15-$30/month.

Safety notes

Can cause mild GI upset (nausea, cramping, loose stools) especially on an empty stomach - always take with food. May slow heart rate slightly; caution with bradycardia medications. Avoid in pregnancy and breastfeeding. Allow 3 months before assessing full effect.

Drug & supplement interactions

  • Always tell your doctor or pharmacist about any supplements you take.
  • Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
  • Herbal remedies can affect how the body absorbs or metabolises drugs.
  • Check drugs.com interactions checker before starting.

This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.