ingestible · for immune support
Astragalus
Reviewed by the Nimbera editorial team · Last updated May 2026
How to use
Take 500-1500 mg of astragalus root extract (standardized to 0.4% astragalosides) daily. Available as capsules, tincture, or as part of adaptogenic blends. Traditional use involves decocting 9-30 g of dried root as tea. Often cycled 8-12 weeks on, 2-4 weeks off for long-term immune support.
How it works
Astragalus polysaccharides and astragalosides activate macrophages, increase natural killer cell activity, stimulate T-lymphocyte proliferation, and upregulate interferons. Astragaloside IV demonstrates telomerase activation, potentially supporting immune cell longevity. Astragalus also has adaptogenic properties that reduce cortisol-mediated immune suppression.
Where to buy
Jarrow Formulas Astragalus ($15-20 for 100 caps), NOW Foods Astragalus ($10-15 for 100 caps), Gaia Herbs Astragalus Supreme ($25-35). Available at health food stores, Amazon, and iHerb.
Typical cost: $10-25/month
Safety notes
Avoid during active autoimmune flare-ups or if taking immunosuppressants, as astragalus may counteract them. Use caution during acute illness with fever (traditional contraindication). Limited data in pregnancy and lactation - avoid unless supervised. May interact with cyclophosphamide chemotherapy.
Drug & supplement interactions
- Always tell your doctor or pharmacist about any supplements you take.
- Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
- Herbal remedies can affect how the body absorbs or metabolises drugs.
- Check drugs.com interactions checker before starting.
Clinical source
Yang L et al. 2025 - Phytomedicine (PMID 40208321)This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.