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ingestible · for stress & anxiety

Ashwagandha Root Extract

Reviewed by the Nimbera editorial team · Last updated May 2026

Moderate evidence$15-35

How to use

Take 300-600mg of a standardized ashwagandha extract (KSM-66 or Sensoril) daily, in the morning or split into two doses. Take consistently for at least 6-8 weeks before evaluating effect.

How it works

Classified as an adaptogen - a compound that helps buffer the physiological stress response. Multiple RCTs show significant reductions in cortisol levels, perceived stress scores (PSS), and anxiety ratings compared to placebo.

Where to buy

Health food stores and supplement retailers. Look for KSM-66 or Sensoril specifically - these are standardized, clinically tested extracts.

Typical cost: $15-35

Safety notes

Can cause drowsiness in some people - take in the morning if this is an issue. Avoid with thyroid disorders, autoimmune conditions, or pregnancy. May interact with thyroid medications and immunosuppressants.

Drug & supplement interactions

  • Always tell your doctor or pharmacist about any supplements you take.
  • Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
  • Herbal remedies can affect how the body absorbs or metabolises drugs.
  • Check drugs.com interactions checker before starting.

Clinical source

Medicine (Baltimore) RCT; Journal of Clinical Psychiatry

This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.