ingestible · for post-viral recovery (long covid)
Ashwagandha (Withania somnifera)
Reviewed by the Nimbera editorial team · Last updated May 2026
How to use
Take 300-600 mg of a standardized KSM-66 or Sensoril extract daily, divided into one or two doses. Take with meals. Use for 8-12 week cycles, then take a 4-week break before resuming.
How it works
Post-viral fatigue involves HPA axis dysregulation - blunted cortisol rhythms, elevated inflammatory signals, and disrupted stress hormone cycling. Ashwagandha's withanolide compounds modulate the HPA axis to normalize cortisol patterns, reduce inflammatory cytokines, and support mitochondrial function.
Where to buy
Health stores, Amazon, supplement retailers. Brands: KSM-66 Ashwagandha (licensed ingredient in many brands), Jarrow Ashwagandha, Gaia Herbs Ashwagandha Root.
Typical cost: $15-$35 per month
Safety notes
May cause sedation in some individuals - avoid driving if drowsy. Thyroid-stimulating effects possible - people with hyperthyroidism or on thyroid medication should consult their doctor. Not recommended during pregnancy. Rare cases of liver injury have been reported with high doses - use recommended doses only.
Drug & supplement interactions
- Always tell your doctor or pharmacist about any supplements you take.
- Interactions can occur with prescription medications, blood thinners, and immunosuppressants.
- Herbal remedies can affect how the body absorbs or metabolises drugs.
- Check drugs.com interactions checker before starting.
Clinical source
PubMed - Gopukumar et al. 2024This information is compiled from primary clinical literature and is for informational purposes only. It is not a substitute for professional medical advice. Read our full disclaimer.